[W] FEED STUFF ABOUT

Be pandemic Hero

Sheer Computation might win this battle

Lets Stop sitting on our @S&.

Let's face it! yes, it is very important to stay at home and not become a potential Carrier of the disease, But ask yourself isn't its a measure for your safety?
It's a crucial step in breaking the chain of infection. But its also a very obvious step in saving your life from COVID-19. So, what are you doing really?
I am not telling you to head outside!!!, let's be Rational.
What I am telling you is that you can be useful at home even, you can contribute in the current research going on for the Vaccine of COVID-19, No I am not asking for money, Nor am I telling you to donate your younger sibling for the research (it's tempting though).

Folding@HOME is a distributed computing project for simulating protein dynamics, including the process of protein folding and the movements of proteins implicated in a variety of diseases. It brings together citizen scientists who volunteer to run simulations of protein dynamics on their personal computers. Insights from this data are helping scientists to better understand biology and providing new opportunities for developing therapeutics.
If by chance you have mined for a Crypto Currency, then you sort of understand how it works (only it is not that resource-hungry). What happens is we provide the computational power on rent to a central pool which has many of clients like us, and what it does is it divides a complex problem among all the connected clients to solve a complex problem that is when solved a cryptocurrency is born and this is then rewarded among the connected clients.
Folding@HOME follows a similar Model, But instead of solving problems for mining Cryptos, it Solves problems for better Understanding the Protines and diseases So, the bottom line is together we can do it.


Distributed Computing

Distributed computing is a model in which components of a software system are shared among multiple computers to improve efficiency and performance.

Distributed Computing

In the Least of Steps, it is like this:


More on Folding@HOME

According to Folding@Home, the combined power of the network broke 1,000,000,000,000,000,000 operations per second – or one “exaflop” – on 25 March.
That is six times more powerful than the current world’s fastest traditional supercomputer(IBM Summit).



Enough, Lets Start Folding!

Process of getting up with Folding@HOME is a Simple one. Just get to there website and download the client of your Platform(Windows, Mac, Linux, Android) its on all of them.
Download Folding@HOME

Once downloaded and installed you can run it and be a Proud Quarantine Guy/Gal, who is not only sitting on his @S&.
Well, I am one Such Proud Person ;)

Folding@HOME Screenshot


Note Before Reading further

The Main goal of this Post was to make you aware about Folding@HOME, and that is it. if you dont want to be blasted with biology jargons its time to head in the bottom like, share, comment and be on your merry way :)
As i am acctaully Planning on adding just a pinch of Biology :P


Eat Orangesss

This is advice for this pandemic. See I am not going to go deep in molecular biology to give you the exact reasons (transcription, Translations, mRNA, tRNA ETC), but I will give you enough reasons to follow this advice.
But I want you to know your way around basic Chemistry and Biology (till 12th Standard).
Okay, Fingers crossed let's get started.

cofactor causing trouble

Our body has a cofactor Enzyme called NADPH oxidase (Nicotinamide adenine dinucleotide phosphate), it is used to donate electrons and hydrogens to reactions as a catalyst, what it does as a by-product is created O2- which is just an oxygen molecule with an extra electron also called as SuperOxide.
However, SuperOxides is not Good for our body functions, as it is super reactive due to the charge it is carrying, and cause inflammation and other issues. it can also be converted to H2O2 if provided by another electron.
we also have a hormone named Angiotensin 2, produced by our liver but unfortunately is a promoter of O2- and as a result, if not converted will cause issues, So what our body does is it converts AT-2(Angiotensin 2) into AT-1,7(Angiotensin 1,7) by using an enzyme called ACE2 (Angiotensin-converting enzyme 2), and now AT-1,7 will Block the production of O2-
Now COVID-19 comes into Play, what it does is it binds with the receptor of ACE2 and it disables it. it also recruits Neutrophils/PMNs(polymorphonuclear nucleotides) which also stimulate the production of SuperOxides.
Here is where our Orange comes for the Rescue, See orange is a Citrus fruit which has a tonne of Vitamin C in it, and what Vitamin C Does, it eats SuperOxides and convert it into water. As Sciencedirect.com Puts it "ascorbate(Vitamin C) has been shown to be effective against the superoxide radical anion, hydrogen peroxide, the hydroxyl radical, water-soluble peroxyl radicals and singlet oxygen [1,5]".
Bottom Line is Eat Citrus fruits (Oranges, Lemons, and all the stuff with Vitamin C in it), it will dissolve SuperOxides showing some mercy to your already suffering body.



Please let me Know if it was helpful... :)